Variety of the Wave Change in Compound Muscle Action Potential in an Animal Model.

Abstract

STUDY DESIGN:

Animal study.

PURPOSE:

To review the present warning point criteria of the compound muscle action potential (CMAP) and investigate new criteria for spinal surgery safety using an animal model.

OVERVIEW OF LITERATURE:

Little is known about correlation palesis and amplitude of spinal cord monitoring.

METHODS:

After laminectomy of the tenth thoracic spinal lamina, 2-140 g force was delivered to the spinal cord with a tension gage to create a bilateral contusion injury. The study morphology change of the CMAP wave and locomotor scale were evaluated for one month.

RESULTS:

Four different types of wave morphology changes were observed: no change, amplitude decrease only, morphology change only, and amplitude and morphology change. Amplitude and morphology changed simultaneously and significantly as the injury force increased (p<0.05) Locomotor scale in the amplitude and morphology group worsened more than the other groups.

CONCLUSIONS:

Amplitude and morphology change of the CMAP wave exists and could be the key of the alarm point in CMAP.

• Authors: Zenya Ito, Shiro Imagama, Kei Ando, Akio Muramoto, Kazuyoshi Kobayashi, Tetsuro Hida, Kenyu Ito, Yoshimoto Ishikawa, Mikito Tsushima, Akiyuki Matsumoto, Satoshi Tanaka, Masayoshi Morozumi, Yukihiro Matsuyama, Naoki Ishiguro
• Journal: Asian spine journal (Asian Spine J) Vol. 9 Issue 6 Pg. 952-7 (Dec 2015) ISSN: 1976-1902 [Print] Korea (South)
• PMID: 26713129 (Publication Type: Journal Article)