[Therapeutic potential of micronized purified flavonoid fraction (MPFF) of diosmin and hesperidin in treatment chronic venous disorder].

Abstract

Chronic venous disorder (CVD) is a common illness with high incidence existing especially in Europe and North America. The main goal of micronized purified flavonoid fraction (MPFF) of diosmin and hesperidin is to eliminate the symptoms of CVD (venous pain, fatigue, etc). But MPFF of diosmin and hesperidin has good effectiveness for treatment of venous oedema and venous ulcer too. There are many papers that prove its effectiveness in the experiment and in the microcirculation too. The other indications for MPFF of diosmin hesperidin is hemorrhoidal disease and the accessory treatment of lymphedema. It is proved that this substance could be used as an effective supplementary treatment of symptoms after venous intervention. Only MPFF diosmin and hesperidin received the best recommendation - 1B in the last guidelines for VAD therapy.

• Authors: Lukáš Hnátek
• Journal: Vnitrni lekarstvi (Vnitr Lek) Vol. 61 Issue 9 Pg. 807-14 (Sep 2015) ISSN: 0042-773X [Print] Czech Republic
• Vernacular Title: Terapeutický potenciál mikronizované purifikované flavonoidní frakce (MPFF) diosminu a hesperidinu v rámci léčby chronického žilního onemocnění.
• PMID: 26465280 (Publication Type: Journal Article, Review)

Chemical References

• Diosmin
• Hesperidin

Topics

• Chronic Disease
• Diosmin (therapeutic use)
• Europe
• Hemorrhoids (drug therapy)
• Hesperidin (therapeutic use)
• Humans
• Lymphedema (drug therapy)
• Microcirculation (drug effects)
• Treatment Outcome
• Varicose Ulcer (drug therapy)
• Venous Insufficiency (drug therapy)