HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Tuberculosis: pH-Responsive Isoniazid-Loaded Nanoparticles Markedly Improve Tuberculosis Treatment in Mice (Small 38/2015).

Abstract
On page 5066, J. I. Zink, M. A. Horwitz, and co-workers use confocal microscopy to demonstrate the avid uptake of RITC-labeled mesoporous silica nanoparticles loaded with the anti-tuberculosis drug isoniazid (shown here in red) by human macrophages (nuclei stained blue with DAPI) infected with GFP-expressing Mycobacterium tuberculosis (shown here in green).
AuthorsAngela A Hwang, Bai-Yu Lee, Daniel L Clemens, Barbara Jane Dillon, Jeffrey I Zink, Marcus A Horwitz
JournalSmall (Weinheim an der Bergstrasse, Germany) (Small) Vol. 11 Issue 38 Pg. 5065 (Oct 2015) ISSN: 1613-6829 [Electronic] Germany
PMID26450161 (Publication Type: Journal Article)
Copyright© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Chemical References
  • Isoniazid
Topics
  • Animals
  • Hydrogen-Ion Concentration
  • Isoniazid (therapeutic use)
  • Mice
  • Nanoparticles (chemistry)
  • Tuberculosis (drug therapy)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: