Patient and procedure selection for the prevention of prosthesis-patient mismatch following aortic valve replacement.

Abstract

Prosthesis-patient mismatch (PPM) is frequent following surgical aortic valve replacement (SAVR) and is associated with an increased risk of morbidity and mortality. Preventive strategies to avoid or minimise PPM should be implemented in patients who are at high risk (i.e., patients with a small aortic annulus or those undergoing a valve-in-valve procedure within a small surgical bioprosthesis) and/or vulnerable to PPM (i.e., depressed left ventricular [LV] systolic function, severe LV hypertrophy, concomitant mitral regurgitation, and paradoxical low-flow, low-gradient aortic stenosis). Recent studies suggest that transcatheter aortic valve replacement (TAVR) may be superior to SAVR for the prevention of PPM and associated adverse cardiac events, particularly in the subset of patients with a small (<21 mm) aortic annulus. However, further randomised studies are needed to confirm the potential superiority of TAVR for this purpose.

• Authors: Philippe Pibarot, Marie-Annick Clavel, Abdellaziz Dahou
• Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology (EuroIntervention) Vol. 11 Suppl W Pg. W106-9 (Sep 2015) ISSN: 1969-6213 [Electronic] France
• PMID: 26384172 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Aortic Valve (physiopathology, surgery)
• Aortic Valve Stenosis (diagnosis, physiopathology, surgery, therapy)
• Cardiac Catheterization (adverse effects, instrumentation)
• Heart Valve Prosthesis
• Heart Valve Prosthesis Implantation (adverse effects, instrumentation)
• Humans
• Patient Selection
• Prosthesis Design
• Risk Assessment
• Risk Factors
• Treatment Outcome