[Primary hyperparathyroidism in patients with bilateral nephrolithiasis].

Abstract

Experience in the diagnosis and treatment of the renal form of primary hyperparathyroidism in 57 patients with bilateral nephrolithiasis was summed up. The main diagnostic criterion was the detection of biochemical changes in the blood and urine (hypercalcemia, hypophosphatemia, hypercalciuria) and the use of some tests (Howard's test and parathyroidin test). Parathyroidectomy was performed after establishing diagnosis. A new stage in therapy of such patients was a study of renal function and phosphocalcium metabolism after parathyroidectomy. The improvement of some indices (an increase in glomerular filtration, urea excretion with urine and relative urine density, and a decrease in hypercalciuria and hyperphosphaturia) indicated the effectiveness of surgical intervention for primary hyperparathyroidism in patients with bilateral nephrolithiasis. It was also confirmed by a decrease in lithogenic relapse after parathyroidectomy.

• Authors: P S Serniak, V N Guzenko, E M Berko
• Journal: Problemy endokrinologii (Probl Endokrinol (Mosk)) 1989 Sep-Oct Vol. 35 Issue 5 Pg. 50-2 ISSN: 0375-9660 [Print] Russia (Federation)
• Vernacular Title: Pervichnyĭ giperparatireoz u bol'nykh dvustoronnim nefrolitiazom.
• PMID: 2587527 (Publication Type: Comparative Study, English Abstract, Journal Article)

Topics

• Arteries (surgery)
• Follow-Up Studies
• Humans
• Hyperparathyroidism (complications, diagnosis, metabolism, surgery)
• Kidney (surgery)
• Kidney Calculi (etiology, metabolism, surgery)
• Parathyroid Glands (surgery)
• Recurrence
• Thyroid Gland (blood supply)