HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Treatment of persistent postmastectomy pain with 5% Lidocaine medicated plaster].

Abstract
Persistent postmastectomy pain (PPMP) syndrome is characterized by neuropathic pain that develops following surgery in breast cancer patients. The reported incidence of PPMP ranges between 30% and 50% and is estimated to increase as the number of women surviving cancer continues to rise. Though effective, today's drug treatments are poorly tolerated, limiting their use and reducing adherence to therapy. Since neuropathic pain is localized, international guidelines suggest that topical treatment with 5% Lidocaine medicated plaster either alone or combined with systemic drugs can be considered for pain management. In this retrospective study we reviewed the medical records of 11 patients treated with 5% lidocaine medicated plaster for moderate-to-severe PPMP at our institute between November 2013 and October 2014. Analysis showed that treatment with 5% Lidocaine medicated plaster, either alone or in combination with systemic drugs, achieved significant pain control already after the first week of therapy. The effectiveness and tolerability of 5% Lidocaine medicated plaster we observed suggests that it is a viable option in the management of PPMP.
AuthorsM E Cruto, E Baricocchi, M Battistella, F Bona, G Giacoletto, A Iacobellis, N Moselli, G Palomba, E Sardo, M Savojardo, L Suita, E Zocca, F Debernardi
JournalMinerva chirurgica (Minerva Chir) Vol. 70 Issue 2 Pg. 147-53 (Apr 2015) ISSN: 0026-4733 [Print] Italy
Vernacular TitleTrattamento del "persistent postmastectomy pain" con Lidocaina cerotto 5%.
PMID25815700 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Anesthetics, Local
  • Lidocaine
Topics
  • Administration, Cutaneous
  • Anesthetics, Local (administration & dosage)
  • Breast Neoplasms (surgery)
  • Female
  • Humans
  • Incidence
  • Lidocaine (administration & dosage)
  • Mastectomy (adverse effects)
  • Middle Aged
  • Pain Measurement
  • Pain, Postoperative (drug therapy, etiology)
  • Retrospective Studies
  • Surveys and Questionnaires
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: