Abstract | OBJECTIVE: The bispectral index (BIS) is a parameter derived by electroencephalography (EEG) which provides a direct measurement of the effects of sedatives and anesthetics on the brain and offers guidance on the adequacy of anesthesia. The literature lacks studies on BIS monitoring in pediatric patients with congenital brain disease undergoing general anesthesia. CLINICAL FEATURES: A 13-year-old child weighing 32kg, suffering from lobar holoprosencephaly, underwent surgery in which the bispectral index (BIS) monitoring the depth of anesthesia showed an abnormal response. Detailed analysis of the trends of BIS values in the different observation times demonstrated sudden falls and repetitive values of BIS likely related to repetitive epileptiform electrical activity caused by sevoflurane. CONCLUSION: The BIS is a very useful monitoring tool for assessing the degree of depth of anesthesia and to analyze the electroencephalographic variations of anesthetics. Particular attention should be given to patients with congenital disorders of the central nervous system in which the BIS may give abnormal responses that do not reflect an accurate assessment of the depth of anesthesia.
|
Authors | Dario Galante, Donatella Fortarezza, Maria Caggiano, Giovanni de Francisci, Dino Pedrotti, Marco Caruselli |
Journal | Revista brasileira de anestesiologia
(Rev Bras Anestesiol)
2015 Sep-Oct
Vol. 65
Issue 5
Pg. 379-83
ISSN: 1806-907X [Electronic] Brazil |
Vernacular Title | Correlação entre monitoração do índice bispectral (BIS) e concentração expirada de sevoflurano em paciente com holoprosencefalia lobar. |
PMID | 25746337
(Publication Type: English Abstract, Journal Article)
|
Copyright | Copyright © 2014 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved. |