Abstract | PURPOSE: The aims of this study were to investigate trends in the prevalence of potentially inappropriate drug use among old people living in geriatric care units in the county of Västerbotten between 2007 and 2013 using six national quality indicators and to assess the impact of medication reviews on those quality indicators. METHODS: Data were collected concerning potentially inappropriate drug use, function in the activities of daily living ( ADL) and cognitive function, using the Multi-Dimensional Dementia Assessment Scale (MDDAS). A comparison was made between the years 2007 and 2013, comprising 2772 and 1902 people, respectively, living in geriatric care in the county of Västerbotten, Sweden. We conducted a parallel investigation of a separate corresponding population in Västerbotten County from 2012, where potentially inappropriate drug use was measured before and after 895 medication reviews which involved a clinical pharmacist. RESULTS: After controlling for age, sex, ADL and cognitive impairment, there was a significant improvement in five out of six quality indicators between 2007 and 2013. While 44% of the people were exposed to one or more potentially inappropriate medications in 2007, this number had declined to 26% by 2013. In the separate population from 2012, the frequency of potentially inappropriate drug use was significantly reduced amongst the people who had a medication review performed. CONCLUSION: The extent of potentially inappropriate drug use declined between 2007 and 2013 according to the quality indicators used. Medication reviews involving clinical pharmacists might be an important factor in reducing potentially inappropriate drug use and improving drug treatment among old people.
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Authors | Maria Gustafsson, Per-Olof Sandman, Stig Karlsson, Ulf Isaksson, Jörn Schneede, Maria Sjölander, Hugo Lövheim |
Journal | European journal of clinical pharmacology
(Eur J Clin Pharmacol)
Vol. 71
Issue 4
Pg. 507-15
(Apr 2015)
ISSN: 1432-1041 [Electronic] Germany |
PMID | 25716889
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Activities of Daily Living
- Aged, 80 and over
- Cognition
(drug effects, physiology)
- Dementia
(physiopathology)
- Drug Utilization
(statistics & numerical data, trends)
- Female
- Homes for the Aged
(statistics & numerical data, trends)
- Humans
- Male
- Potentially Inappropriate Medication List
(statistics & numerical data, trends)
- Prescription Drugs
(administration & dosage, adverse effects)
- Prevalence
- Sweden
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