Lichenoid drug eruption due to imatinib mesylate.

Abstract

Imatinib mesylate is a selective tyrosinase kinase inhibitor which has revolutionized the treatment of chronic myeloid leukemia. It is also used in gastrointestinal stromal tumors and dermatofibrosarcoma protruberans. Cutaneous adverse reactions are the most common nonhematological side effects secondary to imatinib. Nonlichenoid reactions are common, while lichenoid reactions are rare. We report a case of lichenoid drug eruption due to imatinib. As the indications and use of imatinib are increasing, the incidences of adverse effects, including cutaneous ones, are likely to increase. Some of the reactions may be severe enough to warrant discontinuation of the drug. The physicians should be aware of this morphological entity, which is usually benign and does not warrant withdrawal of the drug.

• Authors: Anuradha Bhatia, Bimal Kanish, Paulina Chaudhary
• Journal: International journal of applied & basic medical research (Int J Appl Basic Med Res) 2015 Jan-Apr Vol. 5 Issue 1 Pg. 68-9 ISSN: 2229-516X [Print] India
• PMID: 25664274 (Publication Type: Case Reports)