Pulmonary hypertension in POEMS syndrome: resolution following radiotherapy.

Abstract

Pulmonary hypertension (PH) is defined by the presence of a mean pulmonary artery pressure (mPAP) ≥25 mmHg. It may be idiopathic or arise as a consequence of a number of diverse conditions. PH has been reported in association with POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes), with reversal following systemic treatment with corticosteroids. We report a case of pulmonary hypertension associated with POEMS syndrome treated with radical radiotherapy locally to bone lesions with resolution of systemic disease.

• Authors: Melanie J Brewis, Alistair C Church, Andrew J Peacock, Stephen Thomson, Jane Tighe, Martin K Johnson
• Journal: Pulmonary circulation (Pulm Circ) Vol. 4 Issue 4 Pg. 732-5 (Dec 2014) ISSN: 2045-8932 [Print] United States
• PMID: 25610609 (Publication Type: Case Reports)