How to match the optimal currently available inhaler device to an individual child with asthma or recurrent wheeze.

Abstract

Inhaled medications are the cornerstone of treatment in early childhood wheezing and paediatric asthma. A match between patient and device and a correct inhalation technique are crucial for good asthma control. The aim of this paper is to propose an inhaler strategy that will facilitate an inhaler choice most likely to benefit different groups of children. The main focus will be on pressurised metered dose inhalers and dry powder inhalers. In this paper we will discuss (1) practical difficulties with the devices and with inhaled therapy and (2) the optimal location for deposition of medicines in the lungs, and (3) we will propose a practical and easy way to make the best match between the inhaler device and the individual patient. We hope that this paper will contribute to an increased likelihood of treatment success and improved adherence to therapy.

• Authors: Wim M van Aalderen, Luis Garcia-Marcos, Monika Gappa, Warren Lenney, Søren Pedersen, Richard Dekhuijzen, David Price
• Journal: NPJ primary care respiratory medicine (NPJ Prim Care Respir Med) Vol. 25 Pg. 14088 (Jan 08 2015) ISSN: 2055-1010 [Electronic] England
• PMID: 25568979 (Publication Type: Journal Article, Review)

Chemical References

• Adrenal Cortex Hormones
• Adrenergic beta-2 Receptor Agonists
• Anti-Asthmatic Agents

Topics

• Adrenal Cortex Hormones (administration & dosage)
• Adrenergic beta-2 Receptor Agonists (administration & dosage)
• Algorithms
• Anti-Asthmatic Agents (administration & dosage)
• Asthma (drug therapy)
• Child
• Dry Powder Inhalers
• Equipment Design
• Humans
• Metered Dose Inhalers
• Primary Health Care
• Recurrence
• Respiratory Sounds (drug effects)