[Temporary recommendation for use on off-label baclofen: viewpoint of Prescribers of the CAMTEA system].

Abstract

The use of high dose baclofen for alcohol-dependence emerged in France from 2008 based on empirical findings, and is still off-label. However, due to the rapid increase in this prescribing practice, the French health authorities have decided to frame it using an extraordinary regulatory measure named "temporary recommendation for use" (TRU). Baclofen prescribers from CAMTEA, a regional team-based off-label system for supervising baclofen prescribing, which was developed much prior to the TRU, discuss herein the pros and cons of this measure and the applicability of its different aspects in the daily clinical practice.

• Authors: Benjamin Rolland, Sylvie Deheul, Thierry Danel, Camille Bence, Marie-Christine Blanquart, Alexandre Bonord, Robin Semal, Thierry Briand, Michel Sochala, Christelle Dubocage, François Dupriez, Damien Duquesne, Bernard Gibour, Xavier Loosfeld, Dorothée Henebelle, Michael Henon, Elodie Vernalde, Christian Matton, Jean-Eudes Bacquet, Lucie Molmy, François Sarasy, Nicolas Simioni, Cécile Richez, Laure Gentil-Spinosi, Véronique Vosgien, Jacques Yguel, Thierry Ledent, Marine Auffret, Maroussia Wilquin, Danièle Ziolkowski, Michel Sochala, Sophie Gautier, Régis Bordet, Olivier Cottencin, dispositif CAMTEA
• Journal: Therapie (Therapie) 2015 Mar-Apr Vol. 70 Issue 2 Pg. 235-8 ISSN: 0040-5957 [Print] France
• Vernacular Title: La « recommandation temporaire d'utilisation » sur le baclofène : point de vue des prescripteurs du dispositif CAMTEA.
• PMID: 25487850 (Publication Type: English Abstract, Journal Article)
• Copyright: © 2014 Société Française de Pharmacologie et de Thérapeutique.

Chemical References

• Baclofen

Topics

• Alcoholism (drug therapy)
• Baclofen (administration & dosage, therapeutic use)
• Dose-Response Relationship, Drug
• France
• Humans
• Off-Label Use
• Practice Patterns, Physicians' (statistics & numerical data)