Chronic eczematous
hand dermatoses with and without contact
allergies are complex diseases, which makes it a challenge to select the best treatment and obtain an optimal patient experience and a satisfactory treatment result. The aim of this study was to evaluate retrospectively the clinical effect and patient experience of local treatment with
psoralen plus ultraviolet A (PUVA) soaks and TL01
phototherapy for severe chronic
hand dermatoses, and also to evaluate the quality of life for the subgroup of patients with
allergic contact dermatitis including Compositae
allergy. A retrospective evaluation of results for 94 consecutive patients having received a total of 121 treatment courses with local PUVA soaks or TL01
phototherapy for one of the following diagnoses (n=number of treatment courses):
psoriasis (n=19), hyperk-eratotic hand
eczema (n=27), Pustulosis Palmoplantaris (PPP) (n=22), vesicular
eczema (n=16), Compositae
dermatitis (n=24), and
allergic contact dermatitis (n=13). Moreover, semi-structured interviews with 6 selected patients having multiple contact
allergies including Compositae
allergy were used to evaluate quality of life. As a result, we found that PUVA soaks has good effect in patients with
psoriasis and hyperkeratotic hand
eczema and local
phototherapy for chronic
hand dermatoses is a useful treatment option in selected cases.