Familial Himalayan p wave and left ventricular hypertrabeculation/noncompaction.

Abstract

BACKGROUND:

"Himalayan P waves," are reported in congenital heart disease and cardiomyopathies.

METHODS:

We report a family with hypertrophic cardiomyopathy, Himalayan P waves, extensive focal right atrial wall thickening and left ventricular hypertrabeculation/noncompaction (LVHT).

RESULTS:

The father received a pacemaker and underwent heart transplantation because of hypertrophic cardiomyopathy. His daughters showed Himalayan P waves and right atrial wall thickening. LVHT was diagnosed in sister A at age 23 years and developed in sister B between 42 and 46 years. In sister A the heart rate continuously declined. She refused implantation of a pacemaker and died with 49 years. Sister B, suffers from bradycardia.

CONCLUSIONS:

Himalayan P waves are due to focal right atrial wall thickening, may be familially and associated with LVHT.

• Authors: Claudia Stöllberger, Marion Avanzini, Peter Siostrzonek, Peter Kühn, Walther-Benedikt Winkler, Josef Finsterer
• Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc (Ann Noninvasive Electrocardiol) Vol. 20 Issue 2 Pg. 181-6 (Mar 2015) ISSN: 1542-474X [Electronic] United States
• PMID: 24724986 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2014 Wiley Periodicals, Inc.

Topics

• Adult
• Cardiomyopathy, Hypertrophic (complications, diagnosis, surgery)
• Electrocardiography (methods)
• Fatal Outcome
• Female
• Genetic Predisposition to Disease
• Heart Defects, Congenital (complications, diagnosis, surgery)
• Heart Transplantation
• Humans
• Male
• Middle Aged
• Pacemaker, Artificial
• Ventricular Dysfunction, Left (complications, diagnosis, surgery)
• Young Adult