Surgery for rectal cancer-what is on the horizon?

Abstract

The management of rectal cancer has improved considerably in recent decades. Surgery remains the cornerstone of the treatment. However, the role of preoperative imaging has made it possible to optimize the treatment plan in rectal patients. Neoadjuvant treatment may be indicated in efforts to sterilize possible tumor deposits outside the surgical field, or may be used to downsize and downstage the tumor itself. The optimal sequence of treatment modalities can be determined by a multidisciplinary team, who not only use pretreatment imaging, but also review pathologic results after surgery. The pathologist plays a pivotal role in providing feedback about the success of surgery, i.e., the distance between the tumor and the circumferential resection margin, the quality of surgery, and the effect of neoadjuvant treatment. Registry and auditing of all treatment variables can further improve outcomes. In this century, rectal cancer treatment has become a team effort.

• Authors: Thomas A Vermeer, Ricardo G Orsini, Harm J T Rutten
• Journal: Current oncology reports (Curr Oncol Rep) Vol. 16 Issue 3 Pg. 372 (Mar 2014) ISSN: 1534-6269 [Electronic] United States
• PMID: 24488545 (Publication Type: Journal Article, Review)

Topics

• Disease Management
• Humans
• Neoadjuvant Therapy (methods)
• Neoplasm Staging
• Rectal Neoplasms (pathology, surgery)
• Registries