Abstract | BACKGROUND AND PURPOSE: The efficacy and safety of different antiplatelet regimes for prevention of stroke in patients at high risk were investigated in a systematic review and meta-analysis. METHODS: We searched the Cochrane Central Register of Controlled Trials, MEDLINE, and Web of Science. Twenty-two studies comprising 173 371 patients were included. RESULTS: CONCLUSIONS: CLINICAL TRIAL REGISTRATION URL: http://www.crd.york.ac.uk/prospero. Unique identifier: CRD42011001596.
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Authors | Ghazaleh Gouya, Jasmin Arrich, Michael Wolzt, Kurt Huber, Freek W A Verheugt, Paul A Gurbel, Agnes Pirker-Kees, Jolanta M Siller-Matula |
Journal | Stroke
(Stroke)
Vol. 45
Issue 2
Pg. 492-503
(Feb 2014)
ISSN: 1524-4628 [Electronic] United States |
PMID | 24368560
(Publication Type: Journal Article, Meta-Analysis, Review, Systematic Review)
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Chemical References |
- Piperazines
- Platelet Aggregation Inhibitors
- Receptors, Purinergic P2
- Thiophenes
- Clopidogrel
- Prasugrel Hydrochloride
- Ticagrelor
- Adenosine
- Ticlopidine
- Aspirin
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Topics |
- Adenosine
(analogs & derivatives, therapeutic use)
- Aged
- Aspirin
(therapeutic use)
- Cerebral Hemorrhage
(epidemiology)
- Cerebrovascular Disorders
(prevention & control)
- Clopidogrel
- Cohort Studies
- Data Interpretation, Statistical
- Drug Therapy, Combination
- Female
- Humans
- Ischemic Attack, Transient
(prevention & control)
- Male
- Middle Aged
- Piperazines
(therapeutic use)
- Platelet Aggregation Inhibitors
(adverse effects, therapeutic use)
- Population
- Prasugrel Hydrochloride
- Randomized Controlled Trials as Topic
- Receptors, Purinergic P2
(drug effects)
- Secondary Prevention
- Stroke
(prevention & control)
- Thiophenes
(therapeutic use)
- Ticagrelor
- Ticlopidine
(adverse effects, analogs & derivatives, therapeutic use)
- Vascular Diseases
(complications, drug therapy)
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