Abstract | AIM: METHODS: Fifteen kidney recipients (male 9, female 6, mean age 40.9 ± 9.3 years), who received a diagnosis of IgA nephropathy by allograft biopsy, were enrolled in this study. Tonsillectomy was performed 44.1 ± 27.1 months after the kidney transplantation. All patients underwent a repeat graft biopsy at 23.8 ± 15.8 months after tonsillectomy. RESULTS: Six patients had microhematuria before tonsillectomy. At 12 months after treatment, the microhematuria disappeared in five of these patients and one patient had mild hematuria. Three patients had severe proteinuria (more than 1.0 g/gCr) before tonsillectomy and improved after treatment. On histological analysis, four patients had acute lesions including cellular or fibrocellular crescents. The acute lesions disappeared after these treatments in all patients. Eleven patients had chronic lesions including global sclerosis, segmental sclerosis and fibrous crescents. The chronic lesion was ameliorated in six patients, unchanged in three and deteriorated in two patients. CONCLUSIONS:
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Authors | Kiyohiko Hotta, Yuichiro Fukasawa, Mayuko Akimoto, Tatsu Tanabe, Hajime Sasaki, Nobuyuki Fukuzawa, Toshimori Seki, Masaki Togashi, Hiroshi Harada |
Journal | Nephrology (Carlton, Vic.)
(Nephrology (Carlton))
Vol. 18
Issue 12
Pg. 808-12
(Dec 2013)
ISSN: 1440-1797 [Electronic] Australia |
PMID | 23941658
(Publication Type: Journal Article)
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Copyright | © 2013 Asian Pacific Society of Nephrology. |
Topics |
- Adult
- Female
- Glomerulonephritis, IGA
(pathology, surgery)
- Humans
- Kidney
(pathology)
- Kidney Transplantation
(adverse effects)
- Male
- Middle Aged
- Recurrence
- Tonsillectomy
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