Abstract | BACKGROUND: METHODS: We used the Kids' Inpatient Database samples from 1997, 2000, 2003, 2006 and 2009 to estimate trends in US hospital discharges of children (0-18 years) for whom diagnosis codes indicated invasive pneumococcal disease, HUS, or both (SpHUS). Univariate and multivariate analyses were based on 2009 discharges. RESULTS: During the 5 study years, annual numbers of US hospital discharges for SpHUS approximately doubled (P = 0.025 for linear trend) and cumulatively totaled an estimated 211 discharges. In 2009, SpHUS accounted for 4.6% (95% confidence interval [CI]: 3.0%-6.7%) of HUS discharges, 0.7% (95% CI: 0.5%-1.0%) of invasive pneumococcal disease discharges and 3.0% (95% CI: 2.0%-3.9%) of discharges for complicated pneumococcal pneumonia. Discharges for SpHUS were more likely than those for other invasive pneumococcal disease to occur in children <3 years of age and to incur longer length of stay and greater hospital charges. SpHUS was independently associated with pneumococcal sepsis/ bacteremia (age-adjusted odds ratio 3.8; 95% CI: 1.9-7.8) and complicated pneumonia (odds ratio 9.2; 95% CI: 4.1-20.7). CONCLUSIONS:
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Authors | Angela F Veesenmeyer, M Bruce Edmonson |
Journal | The Pediatric infectious disease journal
(Pediatr Infect Dis J)
Vol. 32
Issue 7
Pg. 731-5
(Jul 2013)
ISSN: 1532-0987 [Electronic] United States |
PMID | 23838775
(Publication Type: Journal Article)
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Topics |
- Adolescent
- Child
- Child, Preschool
- Female
- Hemolytic-Uremic Syndrome
(epidemiology, microbiology)
- Humans
- Incidence
- Infant
- Infant, Newborn
- Length of Stay
(statistics & numerical data, trends)
- Male
- Pneumonia, Pneumococcal
(complications, epidemiology)
- Prevalence
- Retrospective Studies
- Streptococcus pneumoniae
(isolation & purification)
- United States
(epidemiology)
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