Acute myocardial infarction: can it be a complication of acute organophosphorus compound poisoning?

Abstract

Organophosphorus compounds are used as pesticides and represent a common cause of poisoning in developing countries including India due to their widespread availability and use. Toxicity due to these agents can affect many organs including heart. Here, we report a case of acute organophosphorus poisoning (parathion), followed by acute myocardial infarction; documented by clinical features, electrocardiographic changes, and elevated cardiac enzymes. Myocardial infarction has been rarely reported with organophosphorus compounds exposure, thus awareness of this complication can reduce morbidity and mortality.

• Authors: P Joshi, P Manoria, D Joseph, Z Gandhi
• Journal: Journal of postgraduate medicine (J Postgrad Med) 2013 Apr-Jun Vol. 59 Issue 2 Pg. 142-4 ISSN: 0972-2823 [Electronic] India
• PMID: 23793318 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Arrhythmia Agents
• Antidotes
• Insecticides
• Pralidoxime Compounds
• Parathion
• Atropine
• pralidoxime

Topics

• Adult
• Anti-Arrhythmia Agents (administration & dosage)
• Antidotes (administration & dosage)
• Atropine (administration & dosage)
• Humans
• Insecticides (poisoning)
• Male
• Myocardial Infarction (chemically induced, diagnosis, drug therapy)
• Organophosphate Poisoning (drug therapy)
• Parathion (adverse effects, toxicity)
• Pralidoxime Compounds (administration & dosage)
• Suicide, Attempted
• Treatment Outcome