Acetazolamide-induced cilio-choroidal effusion after cataract surgery: unusual posterior involvement.

Abstract

Idiosyncratic reactions to a large number of drugs have been reported to cause choroidal detachment and secondary angle-closure glaucoma (ACG). We report a case of bilateral acute ACG and peculiar choroidal effusion following administration of oral acetazolamide immediately after cataract surgery. Few cases of acute secondary ACG with choroidal effusion and anterior shift of the lens-iris diaphragm have been associated with acetazolamide compared with other sulfonamides. As far as we are aware, posterior involvement with retinal folds and papillary edema due to acetazolamide has not been described before.

• Authors: Romualdo Malagola, Loredana Arrico, Rossella Giannotti, Luigi Pattavina
• Journal: Drug design, development and therapy (Drug Des Devel Ther) Vol. 7 Pg. 33-6 ( 2013) ISSN: 1177-8881 [Electronic] New Zealand
• PMID: 23378740 (Publication Type: Case Reports, Journal Article)

Chemical References

• Carbonic Anhydrase Inhibitors
• Acetazolamide

Topics

• Acetazolamide (adverse effects, therapeutic use)
• Aged
• Carbonic Anhydrase Inhibitors (adverse effects, therapeutic use)
• Cataract Extraction (methods)
• Choroid Diseases (chemically induced, pathology)
• Ciliary Body (drug effects, pathology)
• Drug Therapy, Combination
• Edema (chemically induced)
• Glaucoma, Angle-Closure (chemically induced)
• Humans
• Male