Follow-up MR findings of spinal foraminal nerve sheath tumors after stereotactic irradiation.

Abstract

PURPOSE:

The purpose of this study was to investigate follow-up MR findings of spinal foraminal nerve sheath tumors after stereotactic irradiation.

MATERIALS AND METHODS:

Thirty-five foraminal nerve sheath tumors in 28 patients who underwent stereotactic radiosurgery (SRS) (n = 28) or stereotactic radiotherapy (SRT) (n = 7) were included. The MR images were reviewed to identify serial changes in tumor volume and intratumoral necrosis. Growth and shrinkage were defined as volume changes of ±19.7 % or more; stability was within ±19.7 %. Transient swelling was defined as shrinkage preceded by significant growth. A tumor with shrinkage or stability was regarded as tumor control.

RESULTS:

Of 35 tumors, 16 (46 %) were stable, 14 (40 %) shrunk, and 5 (14 %) grew. Transient swelling was seen for 13 (37 %) lesions. Newly developed intratumoral necrosis was observed for 19 (54 %) of 35 tumors and was significantly associated with transient swelling (p = 0.039) and with tumor control (p = 0.017). SRS was not significantly associated with transient swelling.

CONCLUSION:

In follow-up MR images of spinal foraminal nerve sheath tumors after stereotactic irradiation, newly developed intratumoral necrosis and transient swelling were often seen. Intratumoral necrosis was associated with transient swelling and tumor control.

• Authors: Hyo Jin Kang, Yoon Joon Hwang, Yong Hoon Kim, Su Young Kim, Byung Hoon Lee, Moon-Jun Sohn
• Journal: Japanese journal of radiology (Jpn J Radiol) Vol. 31 Issue 3 Pg. 192-6 (Mar 2013) ISSN: 1867-108X [Electronic] Japan
• PMID: 23255184 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Adult
• Aged
• Female
• Follow-Up Studies
• Humans
• Magnetic Resonance Imaging
• Male
• Middle Aged
• Necrosis
• Nerve Sheath Neoplasms (pathology, radiotherapy, surgery)
• Radiosurgery (methods)
• Retrospective Studies
• Treatment Outcome
• Tumor Burden