Abstract |
Serglycin is a multifunctional molecule and one of the first proteoglycans to be cloned. In this manuscript, we examine the physiological roles of serglycin in immunity, hemostasis, cell growth, apoptosis, and reproduction. In addition, we review recent studies on the involvement of serglycin in various pathological conditions, including cancer, inflammatory diseases, and platelet disorders.
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Authors | Olivia J Scully, Pei-Jou Chua, Karthik S Harve, Boon-Huat Bay, George W Yip |
Journal | Anatomical record (Hoboken, N.J. : 2007)
(Anat Rec (Hoboken))
Vol. 295
Issue 9
Pg. 1415-20
(Sep 2012)
ISSN: 1932-8494 [Electronic] United States |
PMID | 22807344
(Publication Type: Journal Article, Review)
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Copyright | Copyright © 2012 Wiley Periodicals, Inc. |
Chemical References |
- Inflammation Mediators
- Proteoglycans
- Vesicular Transport Proteins
- serglycin
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Topics |
- Animals
- Apoptosis
(physiology)
- Atherosclerosis
(immunology, metabolism, pathology)
- Cell Enlargement
- Hemostasis
(physiology)
- Humans
- Inflammation Mediators
(blood, metabolism, physiology)
- Neoplasms
(immunology, metabolism, pathology)
- Proteoglycans
(blood, physiology)
- Reproduction
(physiology)
- Vesicular Transport Proteins
(blood, physiology)
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