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Serglycin in health and diseases.

Abstract
Serglycin is a multifunctional molecule and one of the first proteoglycans to be cloned. In this manuscript, we examine the physiological roles of serglycin in immunity, hemostasis, cell growth, apoptosis, and reproduction. In addition, we review recent studies on the involvement of serglycin in various pathological conditions, including cancer, inflammatory diseases, and platelet disorders.
AuthorsOlivia J Scully, Pei-Jou Chua, Karthik S Harve, Boon-Huat Bay, George W Yip
JournalAnatomical record (Hoboken, N.J. : 2007) (Anat Rec (Hoboken)) Vol. 295 Issue 9 Pg. 1415-20 (Sep 2012) ISSN: 1932-8494 [Electronic] United States
PMID22807344 (Publication Type: Journal Article, Review)
CopyrightCopyright © 2012 Wiley Periodicals, Inc.
Chemical References
  • Inflammation Mediators
  • Proteoglycans
  • Vesicular Transport Proteins
  • serglycin
Topics
  • Animals
  • Apoptosis (physiology)
  • Atherosclerosis (immunology, metabolism, pathology)
  • Cell Enlargement
  • Hemostasis (physiology)
  • Humans
  • Inflammation Mediators (blood, metabolism, physiology)
  • Neoplasms (immunology, metabolism, pathology)
  • Proteoglycans (blood, physiology)
  • Reproduction (physiology)
  • Vesicular Transport Proteins (blood, physiology)

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