Abstract |
The seroprevalence of Entamoeba histolytica infection in the residents of seven provinces in China was examined by using an enzyme-linked immunosorbent assay with a crude antigen and a recombinant surface antigen, C-Igl, of the parasites. A total of 1,312 serum samples were investigated. The positivity rates for these two antigens were 11.05% and 6.25%, respectively. There was no significant difference in the seropositivity to E. histolytica between men and women. We used a logistic regression model and maximal-likelihood methods to estimate the prevalence of E. histolytica infection from sequential serologic data. Seropositivity in Sichuan, Guizhou, and Sinkiang Provinces was higher than that in Beijing, Shanghai, and Qinghai Provinces. The present study provides an overview of seropositivity to E. histolytica infection in seven provinces in China and use the logistic regression model estimation method to achieve a more accurate measure of amebiasis prevalence.
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Authors | Bin Yang, Yingdan Chen, Liang Wu, Longqi Xu, Hiroshi Tachibana, Xunjia Cheng |
Journal | The American journal of tropical medicine and hygiene
(Am J Trop Med Hyg)
Vol. 87
Issue 1
Pg. 97-103
(Jul 2012)
ISSN: 1476-1645 [Electronic] United States |
PMID | 22764298
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antigens, Protozoan
- DNA Primers
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Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Antigens, Protozoan
(immunology)
- Base Sequence
- Child
- China
(epidemiology)
- DNA Primers
- Entamoeba histolytica
(immunology, isolation & purification)
- Entamoebiasis
(epidemiology)
- Enzyme-Linked Immunosorbent Assay
- Female
- Humans
- Male
- Middle Aged
- Polymerase Chain Reaction
- Seroepidemiologic Studies
- Young Adult
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