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EED mutants impair polycomb repressive complex 2 in myelodysplastic syndrome and related neoplasms.

AuthorsT Ueda, M Sanada, H Matsui, N Yamasaki, Z-I Honda, L-Y Shih, H Mori, T Inaba, S Ogawa, H Honda
JournalLeukemia (Leukemia) Vol. 26 Issue 12 Pg. 2557-60 (Dec 2012) ISSN: 1476-5551 [Electronic] England
PMID22733077 (Publication Type: Letter, Research Support, Non-U.S. Gov't)
Chemical References
  • EED protein, human
  • Histones
  • EZH2 protein, human
  • Enhancer of Zeste Homolog 2 Protein
  • Polycomb Repressive Complex 2
Topics
  • Adult
  • Amino Acid Sequence
  • Base Sequence
  • Enhancer of Zeste Homolog 2 Protein
  • Female
  • Gene Expression Regulation
  • Histones (metabolism)
  • Humans
  • Male
  • Middle Aged
  • Molecular Sequence Data
  • Mutation (genetics)
  • Myelodysplastic Syndromes (genetics, metabolism, pathology)
  • Myeloproliferative Disorders (genetics, metabolism, pathology)
  • Polycomb Repressive Complex 2 (chemistry, genetics, metabolism)
  • Prognosis
  • Protein Conformation
  • Sequence Homology, Amino Acid

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