Abstract | OBJECTIVE: To report the efficacy, safety, and outcomes through time of the biggest series to our knowledge of pituitary surgery using transcranial, transsphenoidal, and endoscopic techniques. METHODS: An observational, retrospective, and descriptive review was performed of 3004 patients surgically treated by the senior author from 1973 to June 2011 in Mexico City. A sublabial approach was used in 3000 patients, and a transnasal approach was used in the remaining 4 patients. Tumors were classified according to size as microadenomas or macroadenomas. RESULTS: CONCLUSIONS: The sum of this 38-year experience of managing pituitary pathology and its surgical treatment shows the importance of working together with other specialists such as endocrinologists, ophthalmologists, and radiologists. The correct treatment approach for each case must be individually selected. Transsphenoidal surgery is an effective and safe treatment for most patients with pituitary adenoma and could be considered the first-choice therapy in all cases except for prolactinomas that respond to pharmacologic therapy ( dopamine agonist).
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Authors | Mauro Loyo-Varela, Tenoch Herrada-Pineda, Francisco Revilla-Pacheco, Salvador Manrique-Guzman |
Journal | World neurosurgery
(World Neurosurg)
Vol. 79
Issue 2
Pg. 331-6
(Feb 2013)
ISSN: 1878-8769 [Electronic] United States |
PMID | 22732515
(Publication Type: Journal Article)
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Copyright | Copyright © 2013 Elsevier Inc. All rights reserved. |
Topics |
- Adenoma
(mortality, pathology, surgery)
- Adult
- Endoscopy
- Female
- Humans
- Male
- Neurosurgical Procedures
- Patient Selection
- Pituitary Neoplasms
(mortality, pathology, surgery)
- Retrospective Studies
- Survival Rate
- Treatment Outcome
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