Effects of heparin versus saline solution on intermittent infusion device irrigation.

Abstract

The purpose of this study was to compare the effectiveness of 1 ml of 0.9% sodium chloride with 10 units of heparin in 1 ml sodium chloride solution, both containing benzyl alcohol, in maintaining patency and reducing the incidence of phlebitis in patients with intermittent infusion devices. The subjects (N = 32) were randomly assigned in a double-blind experimental design. Repeated-measures analysis of variance revealed no significant difference between the groups in phlebitis or patency variables. The results from this controlled study would suggest that 0.9% sodium chloride is as effective as 10 units of heparin in sodium chloride solution in maintaining intermittent infusion device patency and preventing phlebitis.

• Authors: J Ashton, V Gibson, S Summers
• Journal: Heart & lung : the journal of critical care (Heart Lung) Vol. 19 Issue 6 Pg. 608-12 (Nov 1990) ISSN: 0147-9563 [Print] United States
• PMID: 2228650 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Benzyl Alcohols
• Sodium Chloride
• Heparin
• Benzyl Alcohol

Topics

• Adult
• Aged
• Benzyl Alcohol
• Benzyl Alcohols (administration & dosage, therapeutic use)
• Catheters, Indwelling
• Double-Blind Method
• Equipment Failure
• Female
• Heparin (administration & dosage, therapeutic use)
• Humans
• Incidence
• Male
• Middle Aged
• Nursing Assessment
• Nursing Records
• Sodium Chloride (administration & dosage, therapeutic use)
• Therapeutic Irrigation
• Thrombophlebitis (epidemiology, nursing, prevention & control)