Improvement of chronic rhinitis under aspirin.

Abstract

In a subset of aspirin-tolerant asthmatics, administration of aspirin improves respiratory symptoms. We present a patient with chronic rhinosinusitis with nasal polyps who exhibited relief of nasal obstruction and nasal discharge and improvement in the sense of smell following oral administration of 150 mg of aspirin daily. Improvement in the patency of the nasal passages was documented by nasal endoscopy and magnetic resonance imaging. Improvement of olfactory function was documented by validated psychophysical olfactory testing and by means of olfactory event-related potentials.

• Authors: Christos Merkonidis, Volker Gudziol, Mariapaola Paola Cecchini, Johannes Gerber, Han-Seok Seo, Claus Bachert, Thomas Hummel
• Journal: Respiratory care (Respir Care) Vol. 57 Issue 3 Pg. 460-3 (Mar 2012) ISSN: 0020-1324 [Print] United States
• PMID: 22005504 (Publication Type: Case Reports, Journal Article)

Chemical References

• Cyclooxygenase Inhibitors
• Aspirin

Topics

• Aspirin (administration & dosage)
• Chronic Disease
• Cyclooxygenase Inhibitors (administration & dosage)
• Humans
• Magnetic Resonance Imaging
• Male
• Middle Aged
• Nasal Mucosa (pathology)
• Nasal Obstruction (drug therapy)
• Rhinitis (diagnosis, drug therapy, physiopathology)
• Smell (drug effects)