[Vitamin D and hypertension].

Abstract

Low levels of vitamin D, defined as levels of 25-hydroxyvitamin D < 20-30 ng/ml, is a prevalent problem in the general population. Besides the classic relation with musculoskeletal disease, vitamin D has been also related to autoimmune diseases, cancer, metabolic diseases or cardiovascular diseases. High blood pressure, as the main cardiovascular risk factor, also has been related to vitamin D deficiency, constituting two prevalent worldwide health problems. Therefore, this article reviews the most important studies that combine both pathologies, the biological mechanism that relate them and the current evidence about the effect of vitamin D supplementation on hypertension.

• Authors: Cayetana Moyano Peregrín, Francisca López Rodríguez, Maria Del Mar Castilla Castellano
• Journal: Medicina clinica (Med Clin (Barc)) Vol. 138 Issue 9 Pg. 397-401 (Apr 14 2012) ISSN: 1578-8989 [Electronic] Spain
• Vernacular Title: Vitamina D e hipertensión arterial.
• PMID: 21703643 (Publication Type: English Abstract, Journal Article, Review)
• Copyright: Copyright © 2011 Elsevier España, S.L. All rights reserved.

Chemical References

• Receptors, Calcitriol
• Vitamin D
• Phosphorus
• Calcium

Topics

• Animals
• Autoimmune Diseases (epidemiology)
• Biotransformation
• Calcium (metabolism)
• Cardiovascular Diseases (epidemiology)
• Comorbidity
• Diet
• Disease Susceptibility
• Humans
• Hypertension (drug therapy, epidemiology, metabolism)
• Kidney (metabolism)
• Mortality
• Neoplasms (epidemiology)
• Phosphorus (metabolism)
• Prospective Studies
• Rats
• Receptors, Calcitriol (deficiency, physiology)
• Sunlight
• Vitamin D (metabolism, pharmacokinetics, physiology, therapeutic use)
• Vitamin D Deficiency (epidemiology, physiopathology)