Abstract |
We investigated whether postoperative hyperperfusion in moyamoya disease can be predicted using intraoperative laser Doppler flowmetry and/or thermography. A prospective study was conducted on 27 patients (39 hemispheres) with moyamoya disease who underwent superficial temporal artery-middle cerebral artery ( STA-MCA) bypass. During surgery, regional cerebral blood flow (rCBF) was measured with a laser Doppler flowmeter and the temperature of the cortical surface was measured with an infrared thermograph. Postoperative hyperperfusion was assessed immediately after surgery based on CBF study under sedation ( propofol) as >100% increase in corrected rCBF compared to preoperative values. Postoperative hyperperfusion on CBF was observed in two patients (7.4%). A significant correlation was observed between intraoperative rCBF changes and postoperative rCBF increase (Pearson's method: r=0.555, p=0.0003; simple regression: Y=1.22X+3.289, r (2)=0.308, p=0.0004). Furthermore, the rCBF changes measured by laser Doppler flowmetry were significantly greater in patients with postoperative hyperperfusion (p=0.0193) and CHS (p=0.0193). The present study suggests that intraoperative rCBF measurement using laser Doppler flowmetry may predict a risk of post-EC-IC bypass cerebral hyperperfusion in moyamoya disease.
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Authors | Takakazu Kawamata, Akitsugu Kawashima, Kohji Yamaguchi, Tomokatsu Hori, Yoshikazu Okada |
Journal | Neurosurgical review
(Neurosurg Rev)
Vol. 34
Issue 3
Pg. 355-62; discussion 362
(Jul 2011)
ISSN: 1437-2320 [Electronic] Germany |
PMID | 21643682
(Publication Type: Case Reports, Journal Article)
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Topics |
- Adolescent
- Adult
- Anastomosis, Surgical
- Body Temperature
- Cerebrovascular Disorders
(diagnosis, epidemiology, etiology)
- Child
- Evoked Potentials, Somatosensory
- Female
- Humans
- Intraoperative Period
- Laser-Doppler Flowmetry
- Male
- Middle Aged
- Middle Cerebral Artery
(surgery)
- Monitoring, Intraoperative
(methods)
- Moyamoya Disease
(complications, surgery)
- Muscle Weakness
(etiology)
- Postoperative Care
- Predictive Value of Tests
- Temporal Arteries
(surgery)
- Thermography
- Treatment Outcome
- Young Adult
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