Abstract | BACKGROUND:
Paracetamol poisoning remains a major cause of morbidity and mortality. Clinical care of paracetamol poisoning depends on a range of patient variables and typically involves both medical and nursing care. An integrated care pathway (ICP) is a multidisciplinary management plan that incorporates guidelines and best practice to enhance care and documentation for a specific patient group. Paracetamol overdose is thus amenable to an ICP. AIM: To evaluate the introduction of an ICP on process of care of the paracetamol poisoned patient. METHODS: A retrospective case note review of consecutive patients admitted to the Royal Infirmary of Edinburgh following a paracetamol overdose was conducted. Data were collected for a 3-month period before and after introduction of the ICP to the emergency department and toxicology inpatient unit. RESULTS: The ICP was used in 77% of cases in the time period studied and was associated with improvements in initial documentation of patient assessment (pre-ICP vs post-ICP: 87/161 (54%) vs 101/113 (89%), p<0.0001) and appropriateness of blood sampling (146/161 (91%) vs 111/113 (98%), p=0.01), but no change in timely blood sampling (pre 124/161 (77%) vs post 93/113 (82%)). All aspects of intravenous acetylcysteine administration also significantly improved: administration of acetylcysteine if indicated (pre-ICP vs post-ICP: 57/71 (80%) vs 71/71 (100%), p<0.0001); acetylcysteine commenced in a timely fashion (33/71 (46%) vs 55/71 (77%), p=0.0002); and acetylcysteine correctly prescribed (44/58 (76%) vs 71/71 (100%), p<0.0001). CONCLUSIONS: Implementation of an ICP for paracetamol poisoning significantly improved patient management and helped to standardise inter-professional decision making in this challenging patient group. This is likely to improve patient outcome.
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Authors | Janice M Pettie, Margaret A Dow, Euan A Sandilands, H K Ruben Thanacoody, D Nicholas Bateman |
Journal | Emergency medicine journal : EMJ
(Emerg Med J)
Vol. 29
Issue 6
Pg. 482-6
(Jun 2012)
ISSN: 1472-0213 [Electronic] England |
PMID | 21561983
(Publication Type: Journal Article)
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Chemical References |
- Analgesics, Non-Narcotic
- Acetaminophen
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Topics |
- Acetaminophen
(poisoning)
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Analgesics, Non-Narcotic
(poisoning)
- Critical Care
(methods)
- Critical Pathways
(organization & administration)
- Decision Making
- Delivery of Health Care, Integrated
(organization & administration)
- Female
- Humans
- Interprofessional Relations
- Male
- Middle Aged
- Pilot Projects
- Program Evaluation
- Retrospective Studies
- Young Adult
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