National
malaria management policy is based upon the availability of effective and affordable
antimalarial drugs. This study was undertaken to evaluate the quality of the treatment of uncomplicated
malaria cases in Bangui, an area with multi-drug resistant parasites, at a time preceding implementation of a new therapeutic policy relying on the
artemisinin derivative combined treatment
artemether-lumefantrine. A cross-sectional study was carried out in Bangui city to assess availability of
antimalarial drugs and the performances of health workers in the management of uncomplicated
malaria. Availability of drugs was recorded in all drugs wholesalers (n=3), all Pharmacies in health facilities (n=14), private drugstores (n=15), and on 60 non official drug shops randomly chosen in the city. Despite a limited efficacy at the time of the survey,
chloroquine remained widely available in the official and non official markets.
Artemisinin derivatives used in monotherapy or in combination were commonly sold. In health care facilities, 93% of the uncomplicated
malaria cases were treated in the absence of any laboratory confirmation and the officially recommended treatment,
amodiaquine-
sulfadoxine/pyrimethamine was seldom prescribed. Thus, the national guidelines for the treatment of uncomplicated
malaria are not followed by health professionals in Bangui. Its use should be implemented while a control of importation of drug has to be reinforced.