Adhesive arachnoiditis following lumbar myelography.

Abstract

Late sequelae (adhesive arachnoiditis) have been reported following myelography with the oily contrast medium (Pantopaque) and with the ionic water-soluble contrast media methiodal sodium (Abrodil, Conturex, Kontrast U) meglumine iothalamate (Conray Meglumine) and meglumine iocarmate (Bis-Conray, Dimer-X). Adhesive arachnoiditis has not yet been reported after the use of the nonionic water-soluble contrast medium metrizamide (Amipaque). Thus, this is considered the contrast medium of choice for lumbar myelography. Using the recommended dose of 10 ml with an iodine concentration of 170 mg/ml for this examination, adhesive arachnoiditis is unlikely to occur. Increased osmolality of spinal fluid after injection of contrast medium is related to increased frequency of arachnoiditis.

• Authors: I O Skalpe
• Journal: Spine (Spine (Phila Pa 1976)) Vol. 3 Issue 1 Pg. 61-4 (Mar 1978) ISSN: 0362-2436 [Print] United States
• PMID: 205956 (Publication Type: Journal Article)

Chemical References

• Contrast Media
• Mesylates
• Iophendylate
• Metrizamide
• Iothalamate Meglumine

Topics

• Arachnoiditis (etiology)
• Cerebrospinal Fluid (drug effects)
• Contrast Media (adverse effects)
• Humans
• Iophendylate (adverse effects)
• Iothalamate Meglumine (adverse effects)
• Mesylates (adverse effects)
• Metrizamide (adverse effects)
• Myelography (adverse effects)
• Osmolar Concentration
• Tissue Adhesions