A case report: femoral fracture in a multiple sclerosis patient with vitamin d deficiency--a preventable injury.

Abstract

In this report, we describe the management of a multiple sclerosis patient with a femoral fracture who had severe vitamin D deficiency. After the patient's preoperative laboratory studies revealed a normal platelet count, the orthopedic surgeon performed an intramedullary rod fixation on the patient's left femoral fracture. After the surgery, the diagnosis of vitamin D deficiency was made by measuring the circulating serum concentration of 25-dihydroxyvita-min D (25(OH)D) via Disorin's Vitamin D immunochemiluminometric assay LIASION by LabCorp (Laboratory Corporation of America). The patient's postoperative management included the oral administration of 4000 IU of vitamin D3 in a gel-cap suspension that resulted in an elevation of the blood serum concentration of 25(OH)D to an optimal concentration of >80 nmol/L (32 ng/ml).

• Authors: Richard F Edlich, Shelley S Mason, Jill S Reddig, K Gubler, William B Long 3rd
• Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer (J Environ Pathol Toxicol Oncol) Vol. 29 Issue 1 Pg. 3-5 ( 2010) ISSN: 2162-6537 [Electronic] United States
• PMID: 20528741 (Publication Type: Case Reports, Journal Article)

Chemical References

• Cholecalciferol
• Calcifediol

Topics

• Aged
• Bone Nails
• Calcifediol (blood)
• Cholecalciferol (administration & dosage)
• Femoral Fractures (complications, prevention & control, surgery)
• Fracture Fixation, Intramedullary
• Humans
• Male
• Multiple Sclerosis (blood, complications)
• Postoperative Care
• Vitamin D Deficiency (blood, complications, drug therapy)