Botulinum neurotoxin type-A for primary stabbing headache: an open study.

Abstract

Primary stabbing headache is an ultra-short headache, associated with primary headaches, more prevalent in women and with a poor response to therapy. The effect of botulinum neurotoxin type-A (BoNTA) on primary stabbing headache was investigated in 24 patients. Three patients showed complete remission. Nineteen patients showed a decrease in their primary stabbing headaches that started in the second week, and that was sustained during approximately 63 days. In two patients BoNTA showed no therapeutic effect. The BoNTA seems to be an excellent therapeutic option for primary stabbing headache.

• Authors: Elcio Juliato Piovesan, Helio Ghizoni Teive, Pedro André Kowacs, Lucas Leite da Silva, Lineu Cesar Werneck
• Journal: Arquivos de neuro-psiquiatria (Arq Neuropsiquiatr) Vol. 68 Issue 2 Pg. 212-5 (Apr 2010) ISSN: 1678-4227 [Electronic] Germany
• PMID: 20464287 (Publication Type: Journal Article)

Chemical References

• Neurotoxins
• Botulinum Toxins, Type A

Topics

• Adult
• Botulinum Toxins, Type A (therapeutic use)
• Female
• Headache Disorders, Primary (drug therapy, etiology)
• Humans
• Male
• Middle Aged
• Neurotoxins (therapeutic use)
• Pain Measurement
• Severity of Illness Index
• Treatment Outcome