Normalisation of refractive error after steroid injection for adnexal haemangiomas.

Abstract

A longitudinal study of 27 patients with infantile haemangiomas is reported. It confirmed the efficacy of local steroid injection as a method of treatment; 81.5% of patients showed a marked improvement, with the lesion reducing to 25% or less of its original size. Involution was most marked in the first two weeks but continued for up to four months after injection. Amblyopia was present in 43% of children and was usually the result of induced refractive error rather than obstruction of the visual axis or strabismus. Anisometropia was found in 68% of children, with a high incidence of asymmetric astigmatism on the side of the haemangioma. Following local steroid injection a marked reduction in astigmatism was noted in 53.8% of children, a lesser reduction in 15.4%, and no reduction in 30.8%. Successful treatment of the haemangioma, therefore, may not remove the risk of amblyopia, and regular refraction and visual assessment remain mandatory.

• Authors: A J Morrell, H E Willshaw
• Journal: The British journal of ophthalmology (Br J Ophthalmol) Vol. 75 Issue 5 Pg. 301-5 (May 1991) ISSN: 0007-1161 [Print] England
• PMID: 2036349 (Publication Type: Journal Article)

Chemical References

• Triamcinolone
• Dexamethasone

Topics

• Adolescent
• Amblyopia (etiology)
• Astigmatism (prevention & control)
• Child, Preschool
• Dexamethasone (administration & dosage)
• Drug Therapy, Combination
• Eyelid Neoplasms (complications, drug therapy)
• Female
• Hemangioma (complications, drug therapy)
• Humans
• Infant
• Injections, Intralesional
• Longitudinal Studies
• Male
• Refractive Errors (etiology, prevention & control)
• Triamcinolone (administration & dosage)