Dietary fat and infection in burned animals.

Abstract

Dietary lipids can influence the immune response, chiefly through modulation of eicosanoid synthesis. Previous studies showed that diets high in linoleic or oleic acid significantly improved survival rates, compared with diets high in either saturated fats or omega-3 fatty acids, when fed to mice for 2 to 3 weeks before burn injury. These experiments suggest that neutrophil function in rats is not altered by diets high in either fish or safflower oil before burn injury. Serum opsonization is marginally improved by safflower oil diets for 2 weeks before burn injury but not for 6 weeks before burn injury.

• Authors: M D Peck, C K Ogle, J W Alexander, G F Babcock
• Journal: The Journal of burn care & rehabilitation (J Burn Care Rehabil) 1991 Jan-Feb Vol. 12 Issue 1 Pg. 43-5 ISSN: 0273-8481 [Print] United States
• PMID: 2022680 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Dietary Fats
• Fish Oils
• Opsonin Proteins
• Safflower Oil

Topics

• Animals
• Burns (blood, immunology)
• Dietary Fats (metabolism, pharmacology)
• Fish Oils (pharmacology)
• Male
• Neutrophils (drug effects, physiology)
• Opsonin Proteins (physiology)
• Pseudomonas Infections (prevention & control)
• Rats
• Rats, Inbred Strains
• Safflower Oil (pharmacology)
• Time Factors