Abstract | OBJECTIVE: DESIGN: Literature review and consensus building at a multidisciplinary scientific workshop. CONCLUSION(S): There are major gaps in knowledge regarding the etiologic mechanisms, psychosocial effects, natural history, and medical and psychosocial management of primary ovarian insufficiency. An international research consortium and disease registry formed under the guidance of an umbrella organization would provide a pathway to comprehensively increase basic and clinical knowledge about the condition. Such a consortium and patient registry also would provide clinical samples and clinical data with a goal toward defining the specific pathogenic mechanisms. An international collaborative approach that combines the structure of a patient registry with the principles of integrative care and community-based participatory research is needed to advance the field of primary ovarian insufficiency.
|
Authors | Amber R Cooper, Valerie L Baker, Evelina W Sterling, Mary E Ryan, Teresa K Woodruff, Lawrence M Nelson |
Journal | Fertility and sterility
(Fertil Steril)
Vol. 95
Issue 6
Pg. 1890-7
(May 2011)
ISSN: 1556-5653 [Electronic] United States |
PMID | 20188353
(Publication Type: Consensus Development Conference, Journal Article, Research Support, N.I.H., Extramural, Research Support, N.I.H., Intramural, Research Support, Non-U.S. Gov't, Review)
|
Copyright | Copyright © 2011. Published by Elsevier Inc. |
Topics |
- Adolescent
- Community-Based Participatory Research
(organization & administration)
- Consensus
- Female
- Gynecology
(methods, organization & administration, trends)
- Humans
- Pregnancy
- Primary Ovarian Insufficiency
(therapy)
- Registries
- Time Factors
|