[The use of monopril in elderly patients with arterial hypertension and coronary heart disease].

Abstract

We examined 20 patients (mean age 69.4 yr) with stage II AH and CHD. 13 ones suffered CHD with stable FC II and III angina, two others had myocardial infarction. The patients were given monopril, 10 mg BID (08.00 & 20.00). Those with CHD were additionally treated with cardiket (20 mg BID) or monocinque (20 mg BID). If appropriate, hypothiazide or triampur compositum (25 mg each) was given in the morning. Usual clinical examination was supplemented by dynamic studies and evaluation of clinical symptoms on day 21 after therapy including systolic and diastolic AP, pulse and mean dynamic AD, double product, heart rate, ECG, echoCG, AP and ACG monitoring. The above treatment produced marked antihypertensive and antianginal effects in the absence of adverse events.

• Authors: O A Lednev, R M Zaslavskaia, N D Buniatian, S V Sergeev
• Journal: Klinicheskaia meditsina (Klin Med (Mosk)) Vol. 87 Issue 12 Pg. 48-9 ( 2009) ISSN: 0023-2149 [Print] Russia (Federation)
• PMID: 20135887 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Angiotensin-Converting Enzyme Inhibitors
• Fosinopril

Topics

• Aged
• Angiotensin-Converting Enzyme Inhibitors (administration & dosage)
• Blood Pressure (drug effects)
• Coronary Disease (complications, drug therapy, physiopathology)
• Dose-Response Relationship, Drug
• Electrocardiography (drug effects)
• Female
• Follow-Up Studies
• Fosinopril (administration & dosage)
• Humans
• Hypertension (complications, drug therapy, physiopathology)
• Male
• Surveys and Questionnaires
• Treatment Outcome