Immunology: TL1A in the inflammatory network in autoimmune diseases.

Abstract

Several lines of evidence both from experimental models and from clinical studies reveal that TNF-like ligand 1A (TL1A) and its interaction with death receptor 3 (DR3) is critically involved in the pathogenesis of rheumatoid arthritis and other autoimmune diseases.

• Authors: Jagadeesh Bayry
• Journal: Nature reviews. Rheumatology (Nat Rev Rheumatol) Vol. 6 Issue 2 Pg. 67-8 (Feb 2010) ISSN: 1759-4804 [Electronic] United States
• PMID: 20125169 (Publication Type: News, Research Support, Non-U.S. Gov't)

Chemical References

• Receptors, Tumor Necrosis Factor, Member 25
• Tumor Necrosis Factor Ligand Superfamily Member 15

Topics

• Animals
• Arthritis, Rheumatoid (etiology, metabolism)
• Humans
• Receptors, Tumor Necrosis Factor, Member 25 (metabolism)
• Tumor Necrosis Factor Ligand Superfamily Member 15 (metabolism)