Abstract | BACKGROUND: Though the occurrence of postoperative seroma after incisional hernia repair using mesh reinforcement is very common, little is known about the genesis of seroma formation. The aim of this study was to determine the characteristics of drainage liquid as a potential predictor for the development of seroma after incisional hernia mesh repair. Furthermore, the characteristics of drainage liquid were compared to the characteristics of seroma liquid. METHODS: RESULTS: In 11 patients (29%), seroma formation was present after removal of the drainage. We observed significantly elevated mean drainage volume (148 +/- 64 ml vs. 93 +/- 71 ml; P = 0.014) and significantly reduced pH value (7.26 +/- 0.12 vs. 7.41 +/- 0.23; P = 0.016) and IL-1-RA (100 +/- 71 U/ml vs. 145 +/- 108 U/ml; P = 0.016) in the drainage liquid of patients with seroma formation in comparison to patients without seroma formation. In addition, we found significantly altered concentration of lactate (9.8 +/- 2.0 mmol/l vs. 5.5 +/- 1.4 mmol/l; P < 0.001), P-III-P (24 +/- 13 U/ml vs. 89 +/- 79 U/ml; P = 0.045) and fibronectin (0.10 +/- 0.03 g/l vs. 0.24 +/- 0.13 g/l; P = 0.005) in the drainage liquid in comparison to seroma liquid. CONCLUSIONS: The pH value of wound solution proves to be a reliable predictor for the subsequent presence of seroma formation. Furthermore, our findings implicate that seroma formation cannot be seen as persistent drainage liquid.
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Authors | C D Klink, M Binnebösel, A H Lucas, A Schachtrupp, U Klinge, V Schumpelick, K Junge |
Journal | Hernia : the journal of hernias and abdominal wall surgery
(Hernia)
Vol. 14
Issue 2
Pg. 175-9
(Apr 2010)
ISSN: 1248-9204 [Electronic] France |
PMID | 19998048
(Publication Type: Journal Article)
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Chemical References |
- Polypropylenes
- VyproII
- Polyglactin 910
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Topics |
- Drainage
(methods)
- Exudates and Transudates
(chemistry)
- Female
- Hernia, Ventral
(surgery)
- Humans
- Hydrogen-Ion Concentration
- Male
- Middle Aged
- Polyglactin 910
- Polypropylenes
- Postoperative Complications
(therapy)
- Predictive Value of Tests
- Prospective Studies
- Seroma
(therapy)
- Statistics, Nonparametric
- Surgical Mesh
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