Abstract | OBJECTIVE: To review the update research progress about the treatment of diabetic macular edema and to give helpful guidelines in the treatment of diabetic macular edema based on available evidence to date.Data sources A literature search of all English articles was performed on the online electronic PubMed database dated 1984 to 2009. The keywords searched included: macular edema, therapy, laser coagulation, intravitreal triamcinolone acetonide, vascular endothelial growth factor inhibitor, protein kinase C inhibitor and Pars plana vitrectomy. After finding relevant articles within these search limits, a manual search was conducted through the references from these articles.Study selection Original articles and critical reviews were reviewed and selected to address the stated purpose. RESULTS: CONCLUSIONS: As there has been extensive development in multiple treatments of diabetic macular edema, choice of the most suitable treatment for specific patients becomes important. Combination therapy of laser, pharmacological and surgical treatment modalities may offer an alternative to treatment of diabetic macular edema.
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Authors | Xiao-lu Yang, Kun Liu, Xun Xu |
Journal | Chinese medical journal
(Chin Med J (Engl))
Vol. 122
Issue 22
Pg. 2784-90
(Nov 20 2009)
ISSN: 2542-5641 [Electronic] China |
PMID | 19951615
(Publication Type: Journal Article, Review)
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Chemical References |
- Vascular Endothelial Growth Factor A
- Protein Kinase C
- Protein Kinase C beta
- Triamcinolone Acetonide
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Topics |
- Diabetic Retinopathy
(therapy)
- Humans
- Laser Coagulation
- Macular Edema
(therapy)
- Protein Kinase C
(antagonists & inhibitors)
- Protein Kinase C beta
- Triamcinolone Acetonide
(administration & dosage)
- Vascular Endothelial Growth Factor A
(antagonists & inhibitors)
- Vitrectomy
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