Abstract | UNLABELLED: AIMS: METHODS AND RESULTS: Mean age of the patients was 44.7 years; mean follow-up time was 60.57 months. In fifteen cases (57.7%) R0 resection was performed, while eleven patients (42,3%) received only R1 resection. An average of 1.87 resections was necessary in order to achieve R0 resection. Six patients (23%) received adjuvant radiotherapy and two patients (7.6%) adjuvant chemotherapy following the removal of the primary tumor. Sixteen patients had no local recurrence. Ongoing treatments were needed in the case of ten patients (38.4%) who developed local recurrence. One patient has deceased due to distant metastases. Using statistical methods we examined the effects indicated as prognostic factors in the literature on local recurrence, precisely, the effect of age above 50 years and surgical radicalism. CONCLUSIONS:
Dermatofibrosarcoma protuberans can be successfully treated with multidisciplinary therapy. A larger number of cases and randomized multicenter investigations are needed in order to reach more accurate conclusion.
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Authors | Zoltán Mátrai, Gabriella Liszkay, Vanda Plotár, Zsolt Orosz, Judit Székely, Erika Hitre, Alexandra Bartal, Zoltán Langmár, Katalin Bocs, Ferenc Rényi Vámos, Akos Sávolt, László Tóth |
Journal | Orvosi hetilap
(Orv Hetil)
Vol. 150
Issue 41
Pg. 1894-902
(Oct 11 2009)
ISSN: 0030-6002 [Print] Hungary |
Vernacular Title | Dermatofibrosarcoma protuberans multidiszciplináris kezelésével szerzett hosszú távú eredmények 26 betegnél. |
PMID | 19801356
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Antineoplastic Agents
- Benzamides
- Piperazines
- Pyrimidines
- Imatinib Mesylate
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Antineoplastic Agents
(therapeutic use)
- Benzamides
- Chemotherapy, Adjuvant
- Dermatofibrosarcoma
(drug therapy, pathology, radiotherapy, surgery, therapy)
- Female
- Humans
- Imatinib Mesylate
- Male
- Middle Aged
- Mohs Surgery
- Neoplasm Recurrence, Local
(prevention & control)
- Piperazines
(administration & dosage)
- Pyrimidines
(administration & dosage)
- Radiotherapy, Adjuvant
- Skin Neoplasms
(drug therapy, pathology, radiotherapy, surgery, therapy)
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