Generalized pustular psoriasis in a 6-week-old infant.

Abstract	Generalized pustular psoriasis (GPP) is rare in childhood, especially in early infancy. At this young age, it is essential to make an accurate diagnosis as pustules could be the presentation of serious infectious diseases or unusual dermatologic diseases. We reported clinical manifestations, laboratory examinations, and histopathology findings in a 6-week-old girl with GPP. Acitretin was initiated at 1 mg/kg/day with marked improvement on her psoriasis, and titrated to 0.4 mg/kg/day in the subsequent 6 months without flare. Acitretin proved to be an effective therapeutic option for young infants with GPP.
Authors	Pei-Hsin Chao, Yu-Wen Cheng, Mei-Yung Chung
Journal	Pediatric dermatology (Pediatr Dermatol) 2009 May-Jun Vol. 26 Issue 3 Pg. 352-4 ISSN: 1525-1470 [Electronic] United States
PMID	19706107 (Publication Type: Case Reports, Journal Article)
Chemical References	Keratolytic Agents Acitretin
Topics	Acitretin (therapeutic use) Female Humans Infant Keratolytic Agents (therapeutic use) Psoriasis (diagnosis, drug therapy, pathology)

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