Communicable Diseases (Infectious Diseases)

12/05/2014 - "Vaccination is the most effective means of preventing infectious diseases; however, few vaccines are effective against Streptococcus iniae (S. "
05/23/2014 - "Vaccines represent one of the most compelling examples of how biomedical research has improved society by saving lives and dramatically reducing the burden of infectious disease. "
11/01/2013 - "Vaccines elicit immune responses, provide protection against microorganisms and are considered as one of the most successful medical interventions against infectious diseases. "
10/01/2013 - "During the 20th century, deaths from a range of serious infectious diseases decreased dramatically due to the development of safe and effective vaccines. "
11/01/2008 - "There has been a remarkable progress in the prevention,control and even eradication of infectious diseases with improved hygiene and development of antimicrobials and vaccines. "

01/01/2015 - "Although most bacterial infectious diseases can be treated successfully with the remarkable array of antibiotics, the microbial pathogens continue to be one of the most critical health challenges worldwide. "
02/01/2009 - "It, too, is consistent with the marked increase in the liberalization of social values in the West in the 1950s and 1960s (in part, the sexual revolution), regions that, a generation or two earlier, experienced dramatically reduced infectious diseases as a result of antibiotics, vaccinations, food- and water-safety practices, and increased sanitation. "
01/01/2007 - "Modem science through improved sanitation, vaccination and antibiotics as well as improved social and economical conditions, has eliminated the threat of death from most infectious diseases. "
10/01/2012 - "In selected patients, complicated infectious disease of the aorto-iliac tract may be treated successfully with an endograft and prolonged antibiotics."
10/01/2011 - "In-hospital microbial inspections will lead to: 1)improved rapid diagnostic tests for infectious diseases and evaluation of antibiotic treatment in the early stages of disease; 2) detection of the precise origin of microbes and confirmation of etiological factors; 3) antibiotic susceptibility testing and evaluation of combined effects of antibiotics against multiple drug-resistant bacteria; and 4)genetic analysis and epidemiological statistical analysis for the purpose of infection control in a hospital and surrounding areas."

05/07/2014 - "These results demonstrated that antigen conjugated TMC can induce both systemic and mucosal immune responses after nasal administration and may serve as a convenient, safe and effective vaccine for preventing respiratory infectious diseases."
07/01/1998 - "Although initial work focused on potential applications in infectious disease, it was soon recognized that the antigen-specific Th1 response typically generated by genetic immunization protocols could also be useful for the treatment of allergic disease. "
02/01/2010 - "This technology can be applied to the development of improved serodiagnostic tests, discovery of subunit vaccine antigen candidates, epidemiologic research and vaccine development, as well as providing novel insights into infectious disease and the immune system. "
07/01/2015 - "Thirty surviving patients of the IDWP01 (Infectious Diseases Working Party 1) trial were assessed for antibody levels against the seven antigens of the PCV7 and against two of the PPV23-specific antigens. "
06/01/2015 - "The study of the koala transcriptome has the potential to advance our understanding of its immunome--immunological reaction of a given host to foreign antigens--and to help combat infectious diseases (e.g., chlamydiosis) that impede ongoing conservation efforts. "

01/01/2006 - "Due to its highly parallel approach, DNA microarray technology opens up new possibilities that may be particularly beneficial for laboratory diagnosis of infectious diseases. "
01/01/2013 - "DNA immunization by gene gun against a variety of infectious diseases has yielded promising results in animal models. "
01/01/1998 - "Thus, DNA-based immunization of neonates may prove an effective and safe vaccination strategy for induction of cellular immunity against microbes that cause serious infectious diseases in the early period of life."
10/01/2014 - "When nine bacterial species (65 strains saved in National Institute of Infectious Diseases) were tested, which had been confirmed to possess rmtA, rmtB, or armA by PCR and DNA sequencing, the genes were detected correctly in these bacteria with no false negative or false positive results. "
01/01/2014 - "Intranasal DNA Vaccine for Protection against Respiratory Infectious Diseases: The Delivery Perspectives."

04/01/2005 - "Especially the potential of producing therapeutic antibodies in crops that are routine dietary components of farm animals, such as corn and soy beans, seems to hold promise for future application in the fight against infectious diseases."
08/01/2003 - "Murine monoclonal and sheep polyclonal antibodies (mAbs and pAbs) to feline IFN-gamma (fIFN-gamma) were generated firstly to facilitate further research into the role of cellular immune responses in the control of feline infectious disease, and secondly to enable evaluation of the efficacy of novel immunotherapeutic approaches. "
02/05/2000 - "Topical delivery systems can provide prolonged delivery of antibodies to the vaginal mucosal surface for long-term protection against infectious diseases. "
01/01/1992 - "Secretory antibodies in mucosal surfaces are known to play an essential role in protection against various infectious diseases. "
05/07/2015 - "Here, we highlight a recent study making use of miniaturization and automation in the development of a smartphone-integrated point-of-care diagnostic to detect antibodies to infectious diseases in a global health setting. "

04/15/2004 - "(Col)lectin-based chimeric proteins may thus offer promise for therapy of infectious disease."
06/21/1991 - "As a research tool, recombinant vaccinia viruses are used to synthesize biologically active proteins and analyze structure-function relations, determine the targets of humoral- and cell-mediated immunity, and investigate the immune responses needed for protection against specific infectious diseases. "
04/01/2002 - "Some recent studies have shown the role of some structural components of Mycoplasmas in pathogenesis, such as cytoskeleton proteins and adhesins, and the influence of some genetic characteristics on the development of an infectious disease."
10/01/2015 - "Recognizing that structure-based methods are resource-intensive and often require specialized equipment and training, the NIAID has funded two Structural Genomics Centers to determine structures of infectious disease species proteins with the aim of supporting individual investigators' research programs with structural biology methods. "
10/01/2015 - "Although CNB domain-containing proteins have been identified in many pathogenic organisms, an incomplete understanding of how CNB domains in pathogens differ from other eukaryotic hosts has hindered the development of selective inhibitors for CNB domains associated with infectious diseases. "

04/01/1992 - "Use of antimicrobial agents is highly effective in reduction of morbidity and mortality due to infectious disease. "
01/01/2013 - "Antimicrobial agents have eradicated many infectious diseases and significantly improved our living environment. "
04/01/1985 - "A number of antimicrobial agents have been used successfully to treat patients with chronic infectious diseases in the home health care environment. "
06/01/2007 - "It is my hope that all pharmacists will understand the proper use of antimicrobial agents and thus will assure the effective and safe treatment of patients with infectious diseases."
06/01/2007 - "[PK/PD analysis and proper dosage of antimicrobial agents for effective and safe treatment of infectious diseases]."

05/01/1997 - "DNA vaccines have been demonstrated to be effective in inducing protective cell-mediated immune responses in animal models of infectious disease. "
08/20/1999 - "The immunogenicity and protective efficacy of DNA vaccines have been amply demonstrated in numerous animal models of infectious disease. "
03/09/2012 - "Our study further demonstrates that the SCT serves as a potent platform for DNA vaccines against various infectious diseases."
12/01/2011 - "Thus, the results of these studies may offer new ways to develop DNA vaccines, as well as delivering novel vaccine adjuvants against infectious diseases."
12/01/2011 - "Furthermore, electroporation has been applied to DNA vaccines for infectious diseases to enhance immunogenicity, and the relevant clinical trials have been initiated. "

01/01/2011 - "Recently, these secretions were also reported as a rich source of multiple antimicrobial peptides effective against multidrug resistant strains of bacteria, fungi, protozoa, and virus, providing instructive lessons for the development of new and more efficient nanotechnological-based therapies for infectious diseases treatment. "
12/01/2014 - "Antimicrobial peptides (AMPs) have therapeutic potential against infectious diseases and have the ability to target microbial pathogens within eukaryotic cells. "
04/26/2002 - "Thus, this peptide may provide a useful template for designing novel antifungal peptides useful for the treatment of infectious diseases."
01/01/2006 - "Currently, several studies are exploring the possibility of using these antimicrobial peptides as new therapeutic agents against different infectious diseases."
01/01/2003 - "This article is aimed at providing recent studies in our laboratory for the development of antimicrobial or antiviral peptides derived from mixture-based SCLs using cell-based assays, as well as a short review of the importance of such peptides in the control of infectious diseases. "

01/01/2010 - "the importance of vitamin D for bone health is well known, but emerging evidence also suggests that adequate vitamin D status may also be protective against non-communicable diseases. "
03/01/2015 - "Although some prospective studies show positive results regarding vitamin D on infectious disease, several robust studies are negative. "
01/01/2008 - "These findings are probably still approximately correct, if not on the low side, with respect to vitamin D because of the additional benefits found recently, such as protection against infectious diseases."
03/01/2015 - "This review aims to consolidate data from clinical trials that used vitamin D for the treatment or prevention of infectious disease. "
03/01/2015 - "Observational studies have linked vitamin D status and infectious disease. "

01/01/2015 - "Adoptive T cell immunotherapy has demonstrated clinically relevant efficacy in treating malignant and infectious diseases. "
09/09/2011 - "These findings serve in building a conceptual foundation for the design of improved strategies for adjuvants and immunotherapies against infectious diseases."
01/01/2011 - "The improved understanding of the capabilities of macroautophagy for immunity suggests that this pathway should be harnessed in immunotherapies against infectious diseases."
10/01/2011 - "This article reviews the mechanism of fungi immune reaction, and the interaction between NK cells and fungi, and provides some new ideas for further study on pathogenesis of fungus and other infectious diseases and NK cell adoptively transferred immunotherapy."
11/01/2015 - "The emergence of Ebola virus and multi-drug resistant pathogens, however, may breathe new life into the immunotherapy field as researchers seek non-antibiotic interventions for infectious diseases. "

05/01/1993 - "The development of medicine and chemotherapy and the improvement of sanitary conditions resulted in a marked decrease in infectious diseases. "
03/01/1993 - "These results indicate that chemotherapy with IPM/CS is effective for the treatment of severe infectious diseases accompanied by hematological disorders."
01/27/2011 - "The results will help in the search for alternative drugs to be used in pharmacotherapy, and will contribute to establish safe and effective use of phytomedicines in the treatment of infectious diseases."
10/01/1986 - "Therefore, CPFX appears to be a very useful drug when used for chemotherapy of biliary tract infectious diseases."
10/01/1985 - "Therefore, AZT appears to be very useful drug when used for chemotherapy of infectious diseases in surgery."

11/01/1996 - "Hospitals hosting a BMT Unit must fulfill several requirements which are crucial to guaranteeing the best results when faced with the complexity and aggressiveness of transplantation and possible complications, such as a blood bank, an infectious diseases department, a rehabilitation unit, the availability of consultants, as well as playworkers, teachers, psychologists and social workers. "
01/01/2013 - "In summary, our KIR MLPA assay allows rapid and accurate KIR genotyping and CNV detection, thus rendering improved transplantation programs and oncology treatment feasible, and enables more detailed studies on the role of KIRs in human (auto)immunity and infectious disease. "
01/27/2011 - "Improved technologies for the diagnosis of infectious diseases suggest possible changes to paradigms used in the screening of organ donors to prevent disease transmission with transplantation. "
12/27/2002 - "However, in the recent cohort of patients who underwent transplantation after September 1995, there were no fatal cases of Epstein-Barr virus or PTLD or late mortality thus far, suggesting a benefit from improved infectious disease surveillance using currently available modalities. "
10/01/2014 - "Furthermore, we perform studies towards the most optimal, tailor-made immunosuppressive drug regimen and towards the impact of immunosuppression on infectious diseases; cognitive function and cardiovascular status of kidney transplant recipients. "

01/01/2013 - "Although drugs effective against these infectious diseases are available at present, drastic therapeutics have not been developed yet. "
09/27/2012 - "Induced pluripotent stem cell (iPSC) therapeutics are a promising treatment for genetic and infectious diseases. "
09/10/2012 - "To determine whether an introductory review module using a hybrid-learning approach helped students learn infectious disease management in an anti-infectives therapeutics course. "
01/01/2006 - "Research into the modulation of peptide gene expression in animal models, as well as the optimization of peptide-based therapeutics shows promise for the treatment and prevention of airway infectious diseases."
04/01/2011 - "This report also demonstrates that large-scale production of intein-mediated purification of highly pure and active recombinant PoIFNα is feasible for the purposes of experimental studies, veterinary clinic therapeutics, and swine infectious disease control."

01/01/2012 - "Even though the overall outcome after allogeneic transplant has improved significantly in the last decades, late infectious diseases are still the most important causes of late morbidity and mortality. "
12/01/2008 - "It is emphasized that donor quality represents a continuum of risk rather than "good or bad." A distinction is made between donor factors that generate increased risk of graft failure and factors independent of graft function, such as transmissible infectious disease or donor-derived malignancy, that may preclude a good outcome. "
01/01/2014 - "The pre-transplant workup included several tests for infectious diseases, tests of organ function, radiology studies, and markers of malignancy. "
12/01/2012 - "Relevance of cohort studies for the study of transplant infectious diseases."
02/01/2002 - "To study the extent of these differences, we conducted a survey of the practices surrounding specific infectious diseases at US renal transplant centers. "