Abstract | BACKGROUND: Total esophagogastric dissociation (TED) was first described in 1997 by Bianchi as a new surgical procedure to treat severe gastroesophageal reflux disease ( GERD) in children with neurological impairment. Recently, TED has been proposed in other conditions, such as esophageal atresia, esotracheal cleft, or caustic esophageal lesions. Although the long-term results in terms of GERD control have been previously reported, those regarding the nutritional and metabolic status have never been documented. PATIENTS AND METHODS: All patients without neurological impairment with TED between 1999 and 2004 at Robert Debre Hospital and Jeanne de Flandre Hospital, France, were prospectively investigated, paying particular attention to their metabolic and nutritional status (blood concentration of iron and vitamins A, D, E, and B12; lipid malabsorption; and hyperglycemia test) and growth. RESULTS: CONCLUSIONS: TED is an effective procedure for treatment of GERD. However, nutritional and metabolic complications including dumping syndrome and chronic digestive malabsorption are frequent after TED, especially after enteral nutrition weaning. A long-term follow-up of these patients is thus necessary and prolonged enteral nutrition support is recommended.
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Authors | Chrystèle Madre, Lydia Serhal, Laurent Michaud, Michel Bonnevalle, Pascal de Lagausie, Frédéric Gottrand, Arnaud Bonnard, Jean-Pierre Hugot |
Journal | Journal of pediatric gastroenterology and nutrition
(J Pediatr Gastroenterol Nutr)
Vol. 50
Issue 3
Pg. 280-6
(Mar 2010)
ISSN: 1536-4801 [Electronic] United States |
PMID | 19668010
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adolescent
- Avitaminosis
(etiology)
- Child
- Child, Preschool
- Dumping Syndrome
(etiology, therapy)
- Enteral Nutrition
- Esophagus
(abnormalities, surgery)
- Failure to Thrive
(etiology)
- Female
- Gastroesophageal Reflux
(complications, surgery)
- Humans
- Infant
- Infant, Newborn
- Malabsorption Syndromes
(etiology, therapy)
- Male
- Outcome Assessment, Health Care
- Postoperative Complications
(therapy)
- Respiratory Tract Diseases
(etiology)
- Steatorrhea
(etiology)
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