Abstract | OBJECTIVE: METHODS: To retrospective analyze 10 misdiagnosed cases with Castleman's disease in order to give some suggestions for clinical diagnosis and differential diagnosis. RESULTS: Ten patients with neck giant lymph node hyperplasia underwent surgical treatment after misdiagnosis. There were 8 localized Castleman's disease constituted of 6 cases with hyaline vascular type and 2 cases with mixture type and 2 multicentric Castleman's disease constituted of 1 cases with plasma cell type and 1 cases with mixture type were classified according to the criteria described by Frizzera. Ten cases were diagnosed by secondary operation after misdiagnosis and were clinically characterized by painless neck lymphadenectasis, 2 cases with multicentric Castleman's disease accompanied with aspecific systemic symptom and (or) multi-system damage. Ten cases survived for 4 - 17 years during follow-up periods in which 1 case with plasma cell type, multicentric Castleman's disease was recurrent 2 years later and underwent lymphadenectomy and chemotherapy and have no local recurrence so far. CONCLUSIONS:
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Authors | Shi-hong Ma, Qin-jiang Liu, Jun Wang, Rong Yang |
Journal | Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
(Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi)
Vol. 44
Issue 3
Pg. 223-6
(Mar 2009)
ISSN: 1673-0860 [Print] China |
PMID | 19558862
(Publication Type: Journal Article)
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Topics |
- Adolescent
- Adult
- Biopsy
- Castleman Disease
(diagnosis)
- Diagnosis, Differential
- Diagnostic Errors
- Female
- Humans
- Male
- Middle Aged
- Neck
- Retrospective Studies
- Young Adult
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