Dietary intervention after definitive therapy for localized prostate cancer: results from a pilot study.

Abstract

INTRODUCTION:

Diet has been linked to prostate cancer risk. Dietary modification may inhibit prostate cancer progression.

MATERIALS AND METHODS:

As part of a randomized trial, we analyzed the effect of a diet based intervention on 25 prostate cancer patients who had previously undergone surgery or radiation.

RESULTS AND CONCLUSIONS:

In the intervention arm, vegetable intake increased (p < 0.05), fat intake decreased (p < 0.05), and mean plasma levels of ss-carotene and total carotenoids increased (p < 0.05). In the control arm, there were no significant changes in diet or blood carotenoids. These data support the feasibility of studying dietary interventions as salvage or adjuvant therapy after surgery or radiation for localized prostate cancer.

• Authors: J Kellogg Parsons, Vicky A Newman, James L Mohler, John P Pierce, Shirley Flatt, Karen Messer, James Marshall
• Journal: The Canadian journal of urology (Can J Urol) Vol. 16 Issue 3 Pg. 4648-54 (Jun 2009) ISSN: 1195-9479 [Print] Canada
• PMID: 19497171 (Publication Type: Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Prostate-Specific Antigen

Topics

• Aged
• Aged, 80 and over
• Brachytherapy
• Humans
• Male
• Middle Aged
• Pilot Projects
• Prostate-Specific Antigen (blood)
• Prostatectomy
• Prostatic Neoplasms (diet therapy, radiotherapy, surgery)
• Treatment Outcome