Spectrum of purpura fulminans.

Abstract

Purpura Fulminans is a severe disorder of acute onset with high morbidity and mortality. It is characterized by DIC with thrombocytopenia, hyofibrinogenemia, hypothrombinemia and anemia. It most often occurs in young with sudden appearance of symmetrical, tender, ecchymotic skin lesions usually involving the lower extremities. An infectious and noninfectious etiology has been proposed. Early recognition and early therapy with appropriate antibiotics and heparin is known to limit both morbidity and mortality. This article reports 5 cases of Purpura Fulminans treated at our centre with review of etiology, pathogenesis, clinical features and treatment.

• Authors: A V Lalitha, D Aruna, Anand Prakash, H M Nanjunda Swamy, S D Subba Rao
• Journal: Indian journal of pediatrics (Indian J Pediatr) Vol. 76 Issue 1 Pg. 87-9 (Jan 2009) ISSN: 0973-7693 [Electronic] India
• PMID: 19391008 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Anticoagulants

Topics

• Anti-Bacterial Agents (therapeutic use)
• Anticoagulants (therapeutic use)
• Basal Ganglia Diseases (etiology)
• Female
• Gangrene (etiology, surgery)
• Humans
• Infant
• Male
• Purpura Fulminans (complications, drug therapy, physiopathology)
• Skin Diseases (etiology, surgery)