The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: a review.

Abstract	The recent discovery of two defects (ribose-5-phosphate isomerase deficiency and transaldolase deficiency) in the reversible part of the pentose phosphate pathway (PPP) has stimulated interest in this pathway. In this review we describe the functions of the PPP, its relation to other pathways of carbohydrate metabolism and an overview of the metabolic defects in the reversible part of the PPP.
Authors	M M C Wamelink, E A Struys, C Jakobs
Journal	Journal of inherited metabolic disease (J Inherit Metab Dis) Vol. 31 Issue 6 Pg. 703-17 (Dec 2008) ISSN: 1573-2665 [Electronic] United States
PMID	18987987 (Publication Type: Journal Article, Review)
Chemical References	NADP Ribose Transaldolase Oxygen
Topics	Glycolysis Humans Hypoxia Metabolism, Inborn Errors (diagnosis, genetics) Models, Biological Mutation NADP (metabolism) Neoplasms (diagnosis, metabolism) Oxygen (metabolism) Pentose Phosphate Pathway (physiology) Phenotype Ribose (metabolism) Transaldolase (deficiency, genetics)

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