Femtosecond laser-assisted lamellar keratoplasty: early results.

Abstract

PURPOSE:

To evaluate the outcomes and safety of lamellar keratoplasty (LK) assisted by a femtosecond laser.

METHODS:

Twenty-one eyes of 21 patients affected by different corneal pathologies (5 posttraumatic corneal scar, 3 postkeratitis corneal leucoma, and 13 keratoconus) underwent LK procedures by using a femtosecond laser. The mean thinnest corneal thickness, evaluated with ultrasound corneal pachymetry and with confocal microscopy, was 434.19 +/- 62.60 (SD) microm (range, 333-548 microm). Mean preoperative uncorrected visual acuity was 0.09 +/- 0.28 SD and mean preoperative best spectacle-corrected visual acuity was 0.28 +/- 0.15 SD. A femtosecond laser was used to perform corneal cuts on both donor and recipient corneas. The donor corneal lamella diameters were 0.20-mm larger and thicker than the recipient to restore a physiologic corneal thickness and shape: mean donor diameter was 8.34 +/- 0.28 mm (range, 8.2-8.7 mm) and mean thickness was 352 +/- 40.27 microm (range, 220-400 microm). Mean follow-up was 20.86 +/- 5.76 months (range, 12-30 months).

RESULTS:

Early postoperative evaluation showed a clear graft in all cases. A normal corneal pattern topography and a physiologic thickness (mean corneal pachymetry, 542.48 +/- 33.20 microm) and transparency were restored. Twelve months after surgery, the mean postoperative uncorrected visual acuity was 0.45 +/- 0.34 SD, and the mean best spectacle-corrected visual acuity was 0.63 +/- 0.16 SD.

CONCLUSIONS:

Although the numbers in our study are small, our early results indicate that femtosecond laser-assisted lamellar keratoplasty shows promise as a safe and effective surgical choice in the treatment of various corneal pathologies.

• Authors: Luigi Mosca, Romina Fasciani, Ciro Tamburelli, Luca Buzzonetti, Laura Guccione, Erika Mandarà, Emilio Balestrazzi
• Journal: Cornea (Cornea) Vol. 27 Issue 6 Pg. 668-72 (Jul 2008) ISSN: 1536-4798 [Electronic] United States
• PMID: 18580258 (Publication Type: Journal Article)

Topics

• Adolescent
• Adult
• Child
• Cornea (diagnostic imaging, pathology)
• Corneal Diseases (surgery)
• Corneal Transplantation (methods)
• Female
• Follow-Up Studies
• Humans
• Lasers, Semiconductor (therapeutic use)
• Male
• Microscopy, Confocal
• Middle Aged
• Prospective Studies
• Suture Techniques
• Treatment Outcome
• Ultrasonography
• Visual Acuity